← All ingredients

TMG (trimethylglycine)

Also called: Betaine, betaine anhydrous

A nutrient that helps your body turn homocysteine back into a useful amino acid. It is not the same as betaine HCl, a digestive aid.

Medical Disclaimer

Supplements can interact with medications and aren't right for everyone, especially during pregnancy or breastfeeding, or with a chronic condition. Ask your provider before you start.

Studied for

  • High homocysteine, often with folate and B12 (with your practitioner)
  • Methylation support
  • Liver health (early research)

Found naturally in

  • Beets
  • Spinach
  • Quinoa
  • Wheat bran and wheat germ
  • Shellfish
What variations of TMG exist?Our top pick, what to skip, and how to read the label

Label red flags

  • A label that just says 'betaine'. Check whether it's betaine anhydrous (TMG) or betaine HCl.
  • Methylation blends that don't list amounts

Check with a provider

  • High cholesterol. TMG can raise LDL cholesterol at higher amounts.
  • Kidney disease
  • Pregnancy or breastfeeding
  • Stomach upset, nausea, or diarrhea

Supplements that contain it

One product in the Lesher Wellness store lists tmg (trimethylglycine) on the label.

Parts of the body it affects

Explore what each area does and the conditions that can affect it.

Illustrations: Servier Medical Art, CC BY 4.0

Dr. Lesher, ND

Ready to find the root cause?

Dr. Lesher is a Naturopathic Doctor who focuses on autoimmune and chronic conditions in women. Since 2020, she's helped hundreds of patients stop managing symptoms and start healing.

Book a consult now