The extra-pure one
Distilled MSM (such as OptiMSM)
Cleaned up by distillation, which removes more impurities. The kind used in many studies.
Good for: Achy joints
What variations of MSM exist?
A sulfur compound found in small amounts in food. It's mainly used for joint comfort and sore muscles. It comes in 3 forms, and they aren't all the same. Here's how they differ.
Medical Disclaimer
For education only. What's right for you depends on your health and your medications, so check with your provider before you start or switch. Book a consult
Our top pick
Every form, in plain words
The extra-pure one
Distilled MSM (such as OptiMSM)
Cleaned up by distillation, which removes more impurities. The kind used in many studies.
Good for: Achy joints
The other pure one
Crystallized MSM
Purified a different way. Fine from a brand that tests for purity.
Good for: Achy joints
The joint combo
MSM with glucosamine or chondroitin
A common joint pairing. Some studies used them together.
Good for: Achy joints
Spotting a good one on the shelf
Look for
- Look for 'Distilled MSM' on the label (the extra-pure one)
Watch out for
- No mention of purity testing
- Joint blends with only a little MSM
Check with your provider first if…
- You take a blood thinner (not well studied together)
- You're pregnant or breastfeeding (not well studied)
- Upset stomach, bloating, loose stools, or headache
In the Lesher Wellness store
2 products in the store have MSM. Here's which form, where the label says.
Medical Disclaimer
Check with your provider before taking any of these, especially if you're pregnant or take medications.
Patient One MediNutritionals
GastroOne Gut Health Formula
100 mg per serving
Vital Nutrients
GI Repair Powder
Ready to find the root cause?
Dr. Lesher is a Naturopathic Doctor who focuses on autoimmune and chronic conditions in women. Since 2020, she's helped hundreds of patients stop managing symptoms and start healing.