Lesher Wellness
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Phosphatidylserine

Also called: PS

A fat-like nutrient that is part of every cell membrane, especially in the brain. It's studied for memory with aging and for keeping stress hormones in check.

Medical Disclaimer

Supplements can interact with medications and aren't right for everyone, especially during pregnancy or breastfeeding, or with a chronic condition. Ask your provider before you start.

Studied for

  • Memory and focus with aging (some studies)
  • Stress and high cortisol (small studies)
  • Recovery from hard exercise (early research)

Found naturally in

  • Your body makes it
  • Organ meats
  • Mackerel, herring, and tuna
  • White beans
  • Soybeans
What variations of phosphatidylserine exist?Our top pick, what to skip, and how to read the label

Label red flags

  • The source (sunflower, soy, or animal) isn't listed
  • Blends that list 'phospholipids' without the PS amount

Check with a provider

  • Taking blood thinners (not well studied together)
  • Taking medicines for memory loss, such as donepezil, or anticholinergic medicines
  • Soy allergy, if it comes from soy
  • Pregnancy or breastfeeding (not well studied)
  • Trouble sleeping or stomach upset at higher amounts

Supplements that contain it

3 products in the Lesher Wellness store list phosphatidylserine on the label.

Medical Disclaimer

Check with your provider before taking any of these, especially if you're pregnant or take medications.

Parts of the body it affects

Explore what each area does and the conditions that can affect it.

Illustration of the human brain

Brain & nerves

Your brain, spinal cord, and nerves carry every signal in your body, from movement and sensation to mood and memory.

Illustration of an adrenal gland sitting on top of a kidney

Adrenal glands

These small glands on top of your kidneys make cortisol, aldosterone, and adrenaline, which manage energy, blood pressure, and your stress response.

Illustrations: Servier Medical Art, CC BY 4.0

Dr. Lesher, ND

Ready to find the root cause?

Dr. Lesher is a Naturopathic Doctor who focuses on autoimmune and chronic conditions in women. Since 2020, she's helped hundreds of patients stop managing symptoms and start healing.

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