The research match
Extract standardized to 70–80% silymarin
Matches the extracts used in research.
Good for: Everyday use
What variations of milk thistle exist?
A seed extract traditionally used to support the liver. Its active compounds, silymarin, act as antioxidants in liver cells. It comes in 3 forms, and they aren't all the same. Here's how they differ.
For education only. What's right for you depends on your health and your medications, so check with your provider before you start or switch. Book a consult
Our top pick
The better-absorbed one
Silybin phytosome
Bound to fats so your body absorbs it better.
Good for: Everyday use
Every form, in plain words
The research match
Extract standardized to 70–80% silymarin
Matches the extracts used in research.
Good for: Everyday use
The better-absorbed one
Silybin phytosome
Bound to fats so your body absorbs it better.
Good for: Everyday use
Usually skip
- The weak powder (Whole seed powder)Low and uneven amounts of the active compounds.
Spotting a good one on the shelf
Look for
- Look for 'Extract standardized to 70–80% silymarin' on the label (the research match)
- Look for 'Silybin phytosome' on the label (the better-absorbed one)
Watch out for
- No silymarin percentage (the active compounds) listed
- 'Liver detox' blends that don't say how much is inside
Check with your provider first if…
- You're allergic to ragweed, daisies, or related plants
- You take diabetes medicine (it may lower blood sugar)
- You take medicines processed by the liver. Go over your list with your provider.
- You have a hormone-sensitive condition (it may act a little like estrogen)
Ready to find the root cause?
Dr. Lesher is a Naturopathic Doctor who focuses on autoimmune and chronic conditions in women. Since 2020, she's helped hundreds of patients stop managing symptoms and start healing.