What variations of myo-inositol exist?

A vitamin-like nutrient that helps cells respond to insulin. It's one of the better-studied supplements for PCOS. It comes in 3 forms, and they aren't all the same. Here's how they differ.

For education only. What's right for you depends on your health and your medications, so check with your provider before you start or switch. Book a consult 

Our top pick

The PCOS staple

Myo-inositol powder

The most studied form for PCOS. The powder dissolves easily and makes larger amounts easy.

Good for: Periods & PMS · Easy to take

Every form, in plain words

Our top pick

The PCOS staple

Myo-inositol powder

The most studied form for PCOS. The powder dissolves easily and makes larger amounts easy.

Good for: Periods & PMS · Easy to take

Also good

The 40-to-1 combo

Myo-inositol plus D-chiro-inositol (40:1)

Matches the ratio used in many PCOS studies.

Good for: Periods & PMS

Spotting a good one on the shelf

Look for

  • Look for 'Myo-inositol powder' on the label (the PCOS staple)

Watch out for

  • Products that don't say which form of inositol is inside
  • Capsules that give only a small share of the amounts used in studies

Check with your provider first if…

  • Pregnancy or trying to conceive. It's studied in pregnancy, but check with your practitioner first.
  • Diabetes, or taking medicines that lower blood sugar
  • Bipolar disorder or taking lithium
  • Can cause gas, nausea, or loose stools at higher amounts

In Dr. Lesher's store

3 products in Dr. Lesher's dispensary have myo-inositol. Here's which form, where the label says.

PCO Px
Restorative Formulations

PCO Px

Has plus D-chiro-inositol (the 40-to-1 combo), good for periods & PMS

150 mg per serving

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Dr. Lesher, ND

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Dr. Lesher is a Naturopathic Doctor who focuses on autoimmune and chronic conditions in women. Since 2020, she's helped hundreds of patients stop managing symptoms and start healing.

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