What variations of glutathione exist?

Your body's main built-in antioxidant, made from three amino acids. It helps the liver process toxins and protects cells from damage. It comes in 4 forms, and they aren't all the same. Here's how they differ.

Medical Disclaimer

For education only. What's right for you depends on your health and your medications, so check with your provider before you start or switch. Book a consult 

Our top pick

The liquid one

Liposomal glutathione

Wrapped in tiny fat bubbles to help it get through digestion. Often a liquid that tastes a bit like sulfur.

  • Also consider
  • Budget-friendly: the make-your-own one (Building blocks (NAC and glycine))

Every form, in plain words

Also good

The liquid one

Liposomal glutathione

Wrapped in tiny fat bubbles to help it get through digestion. Often a liquid that tastes a bit like sulfur.

Also good

The capsule one

S-acetyl glutathione

A version made to hold up better in your gut. Comes in capsules.

Also good

The plain one

Reduced glutathione capsules

The basic version. Much of it breaks down in your gut, though some studies show levels rise over months.

Also good

The make-your-own one

Building blocks (NAC and glycine)

Gives your body what it needs to make its own glutathione. Inexpensive and well studied.

Good for: Budget-friendly

Spotting a good one on the shelf

Look for

  • Look for 'Liposomal glutathione' on the label (the liquid one)

Watch out for

  • Liposomal products that don't say how much glutathione is in each serving
  • Skin-whitening products that promise dramatic results

Check with your provider first if…

  • You have asthma. Don't breathe in glutathione (as from a nebulizer), since it has tightened the airways in some people.
  • You have cancer or are in cancer treatment. Ask your oncology team first.
  • You're pregnant or breastfeeding (not well studied)
  • An upset stomach or a sulfur taste are the most common side effects
Dr. Lesher, ND

Ready to find the root cause?

Dr. Lesher is a Naturopathic Doctor who focuses on autoimmune and chronic conditions in women. Since 2020, she's helped hundreds of patients stop managing symptoms and start healing.

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