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D-mannose

Also called: Mannose

A simple sugar that may help keep E. coli bacteria from sticking to the bladder wall. It's mostly used to help prevent repeat urinary tract infections (UTIs), with mixed results in studies.

Medical Disclaimer

Supplements can interact with medications and aren't right for everyone, especially during pregnancy or breastfeeding, or with a chronic condition. Ask your provider before you start.

Studied for

  • Preventing repeat UTIs (mixed results in studies)
  • Bladder support alongside cranberry

Found naturally in

  • Small amounts in cranberries, apples, peaches, and oranges
What variations of D-mannose exist?Our top pick, what to skip, and how to read the label

Label red flags

  • D-mannose amount per serving not listed
  • Claims to treat an active UTI

Check with a provider

  • UTI symptoms (burning, urgency, fever, or back pain): see your provider. D-mannose doesn't replace antibiotics for an active infection.
  • Diabetes: it's a sugar, so ask your provider and watch your blood sugar when starting
  • Loose stools or bloating can occur at higher doses
  • Pregnancy or breastfeeding: not well studied

Supplements that contain it

2 products in the Lesher Wellness store list d-mannose on the label.

Parts of the body it affects

Explore what each area does and the conditions that can affect it.

Illustrations: Servier Medical Art, CC BY 4.0

Dr. Lesher, ND

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